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What concerns most virologists and scientists is when viruses get into various animal species. There are some animal species, particularly pigs, that are able to take viruses from chickens, viruses from humans, and once these viruses get into pigs they take on new properties or they change.

The genes from each virus mix creating a new strain. You then have a new influenza virus that hasn't been seen before and that is capable of infecting humans and capable of easily transmitting from human to human.

These are the types of viruses that are responsible for global pandemic outbreaks of influenza. We are probably due for another one.

On June 22nd, 2006 the World Health Organization concluded that Indonesia's family cluster incident (May, 2006) of H5N1 avian influenza cases probably involved person-to-person transmission, including one three-person chain. WHO also said the virus had not mutated and did not spread to anyone outside the family, according to the Associated Press (AP). One of the mysteries about the case cluster, the story notes, is why only blood relatives, not spouses, became infected.

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Tracking Avian Flu
(Wash. Post)



FACT:

Avian influenza viruses are found more commonly in water birds (ducks and geese), shorebirds and gulls. Birds such as sparrows and pigeons tend not to be as readily infected. It is not clear why shorebirds are more susceptible.






Pandemic Planning Handbook (PDF)





"The world is failing billions of people. There is no bigger test for humanity than the crisis of global health."
-- Bill Gates (5/2005)

Enhanced Electron Microscopy of the H5N1 virus |  Image Credit©2005-2006 Link up to knowledge:


Over 100 tigers lost in zoo outbeak of H5N1
Died from eating poultry, or euthanized (Thailand) (CIDRAP 11/22/04)

Why all the fuss when so few are infected?
The last global influenza pandemic, in 1968, began with a single
case in Asia; within five months it had spread around the world and killed more than 45,000 people (28,000 Americans).


FAQ about avian influenza
What it is, what the control measures are, how it
is spread and what kinds of vaccines there are,can a pandemic be averted, and is human-to human transmission possible?


FluAid Software
Online modeling tool designed to assist state and local level planners in preparing for the next influenza pandemic by providing estimates of potential impact specific to their locality.

Preparing for the flu
Key Facts About the Flu: How to Prevent the Flu and What To Do If You Get Sick

Scientists speak at Avian Flu Summit
"The world needs to face the fact that a pandemic is most likely inevitable..."

 Ducks' Role in Bird Flu
Can H5N1 hide in ducks without them getting ill?

 Pandemic Influenza Response and Preparedness Plan
PDF documents from the Department of Health and Human Services

The Flu!
Everything you wanted to know about the flu. This extremely informative writing by Dr. J. Kimball explains just about all. A must read. Did you know the human population has absolutely no immunity against any H5 viruses?

Viprovex
Might Homspera save millions?

Outbreaks in North America
Yes there are outbreaks of avian influenza in N.A. in which transmission has occured. H7N3, H7N2, H5N2... just not H5N1.

Guidance for protection of involved persons
Developed in cooperation with the U.S. Dept. of Agriculture

Guidelines for airline travelers
for those flying and persons meeting passengers arriving from areas with avian influenza

Flu needs to be taken seriously...
it looks like a late peak in this year's flu season and doctors say it is a serious disease

The Gravest Possible Danger
U.S. prepares to test bird flu vaccines after United Nations
officials warning that the Asian bird flu outbreak poses the
"gravest possible danger" of becoming a global pandemic.


                           There are reports that the virus has been found in pigs. This is very troubling as simultaneous infection of a pig by a human strain could provide the opportunity for genetic reassortment between the two strains with the creation of an H5 virus able to spread rapidly between humans.


Somewhere, somehow, the bird flu virus is changing while we sleep!

Donors provided $18 million for emergency activities in response to the outbreak over the years 2004-2005, but that is not enough. We know too little about this disease; most especially how it is transmitted and what makes people vulnerable to it. Real time responses are essential, even though -- or, especially because -- the hardest hit countries are the least developed. Networks have to be established that permit the identification of the disease, patients real and suspected must be isolated, and medicines made available both for treatment and prevention. By one estimate, the only producer of vaccine for the current strain of bird flu would need six months to prepare enough medicine to treat 1 million people for five weeks.